Receptor-Interacting Protein Serine-Threonine Kinase 2 MeSH Descriptor Data 2024

MeSH Heading: Receptor-Interacting Protein Serine-Threonine Kinase 2
Tree Number(s): D08.811.913.696.620.682.700.801.500; D12.776.157.057.006.750; D12.776.157.057.500.186.500; D12.776.476.024.139.750; D12.776.476.024.500.186.500; D12.776.476.075.358.750; D12.776.476.563.801.500
Unique ID: D053475
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053475
Scope Note: A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. It can signal by associating with other CARD-signaling adaptor proteins and INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
Entry Term(s): CARD-containing Interleukin (IL)-1 beta Converting Enzyme; CARDIAK; RICK Protein; RIPK2 Protein; Receptor-Interacting Serine-Threonine Kinase 2
Public MeSH Note: 2007; RECEPTOR-INTERACTING PROTEIN SERINE-THEONINE KINASE 2 was indexed under PROTEIN-SERINE-THREONINE KINASES & TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS 2006, & under PROTEIN KINASES 1998-2006
History Note: 2007(1998)
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2021/06/10

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700]
        
        Receptor-Interacting Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700.801]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D08.811.913.696.620.682.700.801.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - CARD Signaling Adaptor Proteins [D12.776.157.057.006]
        
        Apoptotic Protease-Activating Factor 1 [D12.776.157.057.006.124]
        
        B-Cell CLL-Lymphoma 10 Protein [D12.776.157.057.006.140]
        
        Caspase 9 [D12.776.157.057.006.155]
        
        CRADD Signaling Adaptor Protein [D12.776.157.057.006.186]
        
        Nod1 Signaling Adaptor Protein [D12.776.157.057.006.249]
        
        Nod2 Signaling Adaptor Protein [D12.776.157.057.006.500]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.157.057.006.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Adaptor Proteins, Signal Transducing [D12.776.157.057]
      - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.157.057.500]
        
        Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.157.057.500.186]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.157.057.500.186.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - CARD Signaling Adaptor Proteins [D12.776.476.024.139]
        
        Apoptotic Protease-Activating Factor 1 [D12.776.476.024.139.124]
        
        B-Cell CLL-Lymphoma 10 Protein [D12.776.476.024.139.140]
        
        Caspase 9 [D12.776.476.024.139.155]
        
        CRADD Signaling Adaptor Protein [D12.776.476.024.139.186]
        
        Nod1 Signaling Adaptor Protein [D12.776.476.024.139.249]
        
        Nod2 Signaling Adaptor Protein [D12.776.476.024.139.500]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.476.024.139.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Adaptor Proteins, Signal Transducing [D12.776.476.024]
      - Tumor Necrosis Factor Receptor-Associated Peptides and Proteins [D12.776.476.024.500]
        
        Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.476.024.500.186]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.476.024.500.186.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Apoptosis Regulatory Proteins [D12.776.476.075]
      - CARD Signaling Adaptor Proteins [D12.776.476.075.358]
        
        Apoptotic Protease-Activating Factor 1 [D12.776.476.075.358.124]
        
        B-Cell CLL-Lymphoma 10 Protein [D12.776.476.075.358.140]
        
        Caspase 9 [D12.776.476.075.358.155]
        
        CRADD Signaling Adaptor Protein [D12.776.476.075.358.186]
        
        Nod1 Signaling Adaptor Protein [D12.776.476.075.358.249]
        
        Nod2 Signaling Adaptor Protein [D12.776.476.075.358.500]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.476.075.358.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein Serine-Threonine Kinases [D12.776.476.563]
      - Receptor-Interacting Protein Serine-Threonine Kinases [D12.776.476.563.801]
        
        Receptor-Interacting Protein Serine-Threonine Kinase 2 [D12.776.476.563.801.500]

Receptor-Interacting Protein Serine-Threonine Kinase 2 Preferred

Concept UI: M0290667
Scope Note: A RIP serine-theonine kinase that contains a C-terminal caspase activation and recruitment domain. It can signal by associating with other CARD-signaling adaptor proteins and INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.
Terms: Receptor-Interacting Protein Serine-Threonine Kinase 2 Preferred Term
Term UI T662351
Date12/16/2005
LexicalTag NON
ThesaurusID NLM (2007); RICK Protein
Term UI T320672
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); CARDIAK
Term UI T327193
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2007); CARD-containing Interleukin (IL)-1 beta Converting Enzyme
Term UI T327194
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2007); Receptor-Interacting Serine-Threonine Kinase 2
Term UI T424949
Date09/25/2000
LexicalTag NON
ThesaurusID NLM (2007); RIPK2 Protein
Term UI T424950
Date09/25/2000
LexicalTag ABX
ThesaurusID NLM (2007)

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