- Concept UI
- M0492994
- Registry Numbers
- EC 2.7.11.1
- Scope Note
- A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
- Terms
-
Receptor-Interacting Protein Serine-Threonine Kinases
Preferred Term
Term UI
T662348
Date12/16/2005
LexicalTag
NON
ThesaurusID
NLM (2007)
-
RIP Serine-Threonine Kinases
Term UI
T662350
Date12/16/2005
LexicalTag
ABX
ThesaurusID
NLM (2007)
-
RIPK (Ribosome Inactivating Proteins)
Term UI
T001145945
Date11/01/2024
LexicalTag
NON
ThesaurusID
NLM (2025)
-
RIPK Ribosome Inactivating Proteins
Term UI
T001145946
Date11/01/2024
LexicalTag
NON
ThesaurusID
NLM (2025)