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TOR Serine-Threonine Kinases MeSH Descriptor Data 2025


MeSH Heading
TOR Serine-Threonine Kinases
Tree Number(s)
D08.811.913.696.620.682.700.931
D12.776.476.563.931
Unique ID
D058570
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D058570
Scope Note
A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.
Entry Term(s)
FK506 Binding Protein 12-Rapamycin Associated Protein 1
FKBP12-Rapamycin Associated Protein
FKBP12-Rapamycin Complex-Associated Protein
Mammalian Target of Rapamycin
Mechanistic Target of Rapamycin Protein
RAFT-1 Protein
Rapamycin Target Protein
TOR Kinase
TOR Kinases
TOR Serine-Threonine Kinase
Target of Rapamycin Protein
Target of Rapamycin Proteins
mTOR Protein
mTOR Serine-Threonine Kinase
mTOR Serine-Threonine Kinases
Registry Numbers
EC 2.7.11.1
Public MeSH Note
2011; MTOR PROTEIN (now TOR SERINE-THREONINE KINASES) was indexed under PROTEIN KINASES 1995-2010 and under PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR) 1995-2001
History Note
2011
Date Established
2011/01/01
Date of Entry
2010/06/25
Revision Date
2021/05/21
TOR Serine-Threonine Kinases Preferred
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