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Receptor, Transforming Growth Factor-beta Type I MeSH Descriptor Data 2022


MeSH Heading
Receptor, Transforming Growth Factor-beta Type I
Tree Number(s)
D08.811.913.696.620.682.700.789
D12.776.476.563.789
D12.776.543.750.705.852.720.500
D12.776.543.750.750.400.820.750
Unique ID
D000077293
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077293
Scope Note
A transmembrane serine-threonine kinase that forms a heteromeric complex with TYPE II TGF-BETA RECEPTORS to bind TGF-BETA and regulate a variety of physiological and pathological processes including CELL CYCLE ARREST; CELL PROLIFERATION; CELL DIFFERENTIATION; WOUND HEALING; EXTRACELLULAR MATRIX production, immunosuppression and ONCOGENESIS.
Entry Term(s)
Activin Receptor-like Kinase 5
Receptor, TGF-beta Type I
Serine-Threonine-Protein Kinase Receptor R4
TGF-beta RPK
TGF-beta Receptor Protein Kinase
TGF-beta Type I Receptor
TGF-beta Type I Receptors
TGFBR1
TbetaR-I Kinase
Transforming Growth Factor beta Receptor I
Transforming Growth Factor, beta Receptor 1
Type I TGF-beta Receptor
Type I TGF-beta Receptors
Registry Number
EC 2.7.11.30
Public MeSH Note
2019; see TGF-BETA TYPE I RECEPTOR 1995-2018; RECEPTOR, TRANSFORMING GROWTH FACTOR-BETA TYPE I was indexed under PROTEIN-SERINE-THREONINE KINASES and RECEPTORS, TRANSFORMING GROWTH FACTOR BETA 2008-2018; under ACTIVIN RECEPTORS, TYPE I 1994-2018; and under PROTEIN-SERINE-THREONINE KINASES 1994-2001
History Note
2019 (1994)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2021/05/21
Receptor, Transforming Growth Factor-beta Type I Preferred
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