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Transforming Growth Factor beta MeSH Descriptor Data 2022


MeSH Heading
Transforming Growth Factor beta
Tree Number(s)
D12.644.276.374.687
D12.644.276.954.775
D12.776.467.374.687
D12.776.467.942.775
D23.529.374.687
D23.529.942.775
Unique ID
D016212
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016212
Scope Note
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Entry Term(s)
Bone-Derived Transforming Growth Factor
Milk Growth Factor
Platelet Transforming Growth Factor
TGF-beta
TGFbeta
Registry Number
0
NLM Classification #
QU 107
Previous Indexing
Peptides (1983-1988)
Transforming Growth Factors (1989-1990)
Public MeSH Note
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
Online Note
use TRANSFORMING GROWTH FACTORS to search TRANSFORMING GROWTH FACTOR BETA & TGF-BETA 1989-90
History Note
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
Date Established
1991/01/01
Date of Entry
1990/06/29
Revision Date
2015/06/02
Transforming Growth Factor beta Preferred
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