NLM Logo

Transforming Growth Factor beta MeSH Descriptor Data 2024


MeSH Heading
Transforming Growth Factor beta
Tree Number(s)
D12.644.276.374.687
D12.644.276.954.775
D12.776.467.374.687
D12.776.467.942.775
D23.529.374.687
D23.529.942.775
Unique ID
D016212
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016212
Scope Note
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
Entry Term(s)
Bone-Derived Transforming Growth Factor
Milk Growth Factor
Platelet Transforming Growth Factor
TGF-beta
TGFbeta
Registry Numbers
0
NLM Classification #
QU 107
Previous Indexing
Peptides (1983-1988)
Transforming Growth Factors (1989-1990)
Public MeSH Note
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
Online Note
use TRANSFORMING GROWTH FACTORS to search TRANSFORMING GROWTH FACTOR BETA & TGF-BETA 1989-90
History Note
91; was see TRANSFORMING GROWTH FACTORS 1989-90; TGF-BETA was see TRANSFORMING GROWTH FACTORS 1989-90
Date Established
1991/01/01
Date of Entry
1990/06/29
Revision Date
2015/06/02
Transforming Growth Factor beta Preferred
page delivered in 0.152s