MeSH Browser

MeSH Heading: Tumor Necrosis Factors
Tree Number(s): D12.644.276.374.750; D12.776.467.374.750; D23.529.374.750
Unique ID: D048069
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D048069
Scope Note: A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.
Entry Term(s): TNF Receptor Ligands; Tumor Necrosis Factor Superfamily Ligands
Registry Numbers: 0
Public MeSH Note: 2005
History Note: 2005
Entry Combination: antagonists & inhibitors:Tumor Necrosis Factor Inhibitors
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2018/10/10

Entry Combination: antagonists & inhibitors:Tumor Necrosis Factor Inhibitors
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Tumor Necrosis Factors MeSH Descriptor Data 2025