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Tumor Necrosis Factors
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Tumor Necrosis Factors
Tree Number(s)
D12.644.276.374.750
D12.776.467.374.750
D23.529.374.750
Unique ID
D048069
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D048069
Scope Note
A family of proteins that were originally identified by their ability to cause
NECROSIS
of
NEOPLASMS
. Their necrotic effect on cells is mediated through
TUMOR NECROSIS FACTOR RECEPTORS
which induce
APOPTOSIS
.
Entry Term(s)
TNF Receptor Ligands
Tumor Necrosis Factor Superfamily Ligands
Public MeSH Note
2005
History Note
2005
Entry Combination
antagonists & inhibitors:Tumor Necrosis Factor Inhibitors
Date Established
2005/01/01
Date of Entry
2004/07/07
Revision Date
2018/10/10
Entry Combination
antagonists & inhibitors:Tumor Necrosis Factor Inhibitors
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analysis (AN)
biosynthesis (BI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
deficiency (DF)
economics (EC)
genetics (GE)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
physiology (PH)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Growth Differentiation Factor 15 [D12.644.276.374.305]
Hematopoietic Cell Growth Factors [D12.644.276.374.410]
Hepatocyte Growth Factor [D12.644.276.374.420]
Interferons [D12.644.276.374.440]
Interleukin 1 Receptor Antagonist Protein [D12.644.276.374.460]
Interleukins [D12.644.276.374.465]
Leukemia Inhibitory Factor [D12.644.276.374.470]
Lymphokines [D12.644.276.374.480]
Monokines [D12.644.276.374.500]
Oncostatin M [D12.644.276.374.562]
Osteopontin [D12.644.276.374.625]
Thymic Stromal Lymphopoietin [D12.644.276.374.656]
Transforming Growth Factor beta [D12.644.276.374.687]
Tumor Necrosis Factors [D12.644.276.374.750]
CD27 Ligand [D12.644.276.374.750.030]
B-Cell Activating Factor [D12.644.276.374.750.061]
4-1BB Ligand [D12.644.276.374.750.065]
CD30 Ligand [D12.644.276.374.750.092]
CD40 Ligand [D12.644.276.374.750.124]
Cytokine TWEAK [D12.644.276.374.750.155]
Ectodysplasins [D12.644.276.374.750.186]
Fas Ligand Protein [D12.644.276.374.750.249]
Lymphotoxin-alpha [D12.644.276.374.750.500]
Lymphotoxin alpha1, beta2 Heterotrimer [D12.644.276.374.750.505]
Lymphotoxin-beta [D12.644.276.374.750.515]
OX40 Ligand [D12.644.276.374.750.531]
RANK Ligand [D12.644.276.374.750.562]
TNF-Related Apoptosis-Inducing Ligand [D12.644.276.374.750.625]
Tumor Necrosis Factor-alpha [D12.644.276.374.750.626]
Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.644.276.374.750.656]
Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.644.276.374.750.690]
Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.644.276.374.750.720]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Growth Differentiation Factor 15 [D12.776.467.374.305]
Hematopoietic Cell Growth Factors [D12.776.467.374.410]
Hepatocyte Growth Factor [D12.776.467.374.420]
Interferons [D12.776.467.374.440]
Interleukin 1 Receptor Antagonist Protein [D12.776.467.374.460]
Interleukins [D12.776.467.374.465]
Leukemia Inhibitory Factor [D12.776.467.374.470]
Lymphokines [D12.776.467.374.480]
Monokines [D12.776.467.374.500]
Oncostatin M [D12.776.467.374.562]
Osteopontin [D12.776.467.374.625]
Thymic Stromal Lymphopoietin [D12.776.467.374.656]
Transforming Growth Factor beta [D12.776.467.374.687]
Tumor Necrosis Factors [D12.776.467.374.750]
CD27 Ligand [D12.776.467.374.750.030]
B-Cell Activating Factor [D12.776.467.374.750.061]
4-1BB Ligand [D12.776.467.374.750.065]
CD30 Ligand [D12.776.467.374.750.092]
CD40 Ligand [D12.776.467.374.750.124]
Cytokine TWEAK [D12.776.467.374.750.155]
Ectodysplasins [D12.776.467.374.750.186]
Fas Ligand Protein [D12.776.467.374.750.249]
Lymphotoxin-alpha [D12.776.467.374.750.500]
Lymphotoxin alpha1, beta2 Heterotrimer [D12.776.467.374.750.505]
Lymphotoxin-beta [D12.776.467.374.750.515]
OX40 Ligand [D12.776.467.374.750.531]
RANK Ligand [D12.776.467.374.750.562]
TNF-Related Apoptosis-Inducing Ligand [D12.776.467.374.750.625]
Tumor Necrosis Factor-alpha [D12.776.467.374.750.626]
Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.776.467.374.750.656]
Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.776.467.374.750.690]
Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.776.467.374.750.710]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]
Growth Differentiation Factor 15 [D23.529.374.305]
Hematopoietic Cell Growth Factors [D23.529.374.410]
Hepatocyte Growth Factor [D23.529.374.420]
Interferons [D23.529.374.440]
Interleukin 1 Receptor Antagonist Protein [D23.529.374.460]
Interleukins [D23.529.374.465]
Leukemia Inhibitory Factor [D23.529.374.470]
Lymphokines [D23.529.374.480]
Monokines [D23.529.374.500]
Oncostatin M [D23.529.374.562]
Osteopontin [D23.529.374.625]
Thymic Stromal Lymphopoietin [D23.529.374.656]
Transforming Growth Factor beta [D23.529.374.687]
Tumor Necrosis Factors [D23.529.374.750]
CD27 Ligand [D23.529.374.750.030]
B-Cell Activating Factor [D23.529.374.750.061]
4-1BB Ligand [D23.529.374.750.065]
CD30 Ligand [D23.529.374.750.092]
CD40 Ligand [D23.529.374.750.124]
Cytokine TWEAK [D23.529.374.750.155]
Ectodysplasins [D23.529.374.750.186]
Fas Ligand Protein [D23.529.374.750.249]
Lymphotoxin-alpha [D23.529.374.750.500]
Lymphotoxin alpha1, beta2 Heterotrimer [D23.529.374.750.505]
Lymphotoxin-beta [D23.529.374.750.515]
OX40 Ligand [D23.529.374.750.531]
RANK Ligand [D23.529.374.750.562]
TNF-Related Apoptosis-Inducing Ligand [D23.529.374.750.625]
Tumor Necrosis Factor-alpha [D23.529.374.750.626]
Tumor Necrosis Factor Ligand Superfamily Member 13 [D23.529.374.750.656]
Tumor Necrosis Factor Ligand Superfamily Member 14 [D23.529.374.750.690]
Tumor Necrosis Factor Ligand Superfamily Member 15 [D23.529.374.750.710]
Expand All
Collapse All
Tumor Necrosis Factors
Preferred
Concept UI
M0460559
Scope Note
A family of proteins that were originally identified by their ability to cause
NECROSIS
of
NEOPLASMS
. Their necrotic effect on cells is mediated through
TUMOR NECROSIS FACTOR RECEPTORS
which induce
APOPTOSIS
.
Terms
Tumor Necrosis Factors
Preferred Term
Term UI
T572115
Date
02/10/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
TNF Receptor Ligands
Term UI
T572116
Date
02/10/2004
LexicalTag
ACX
ThesaurusID
NLM (2005)
Tumor Necrosis Factor Superfamily Ligands
Related
Concept UI
M0460560
Terms
Tumor Necrosis Factor Superfamily Ligands
Preferred Term
Term UI
T572117
Date
02/10/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
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