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TNF-Related Apoptosis-Inducing Ligand MeSH Descriptor Data 2022


MeSH Heading
TNF-Related Apoptosis-Inducing Ligand
Tree Number(s)
D12.644.276.374.750.625
D12.776.467.374.750.625
D23.529.374.750.625
Unique ID
D053221
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053221
Scope Note
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
Entry Term(s)
Apo-2 Ligand
Apo-2L Protein
CD253 Antigen
TNF Superfamily, Member 10
TRAIL Protein
Tumor Necrosis Factor Ligand Superfamily Member 10
Registry Number
0
Public MeSH Note
2007; TNF-RELATED APOPTOSIS-INDUCING LIGAND was indexed under APOPTOSIS REGULATORY PROTEINS, TUMOR NECROSIS FACTOR-ALPHA and MEMBRANE GLYCOPROTEINS 1996-2006
History Note
2007(2005)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2017/05/24
TNF-Related Apoptosis-Inducing Ligand Preferred
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