Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Lymphotoxin-alpha MeSH Descriptor Data 2025


MeSH Heading
Lymphotoxin-alpha
Tree Number(s)
D12.644.276.374.480.438
D12.644.276.374.750.500
D12.776.467.374.480.438
D12.776.467.374.750.500
D23.529.374.480.438
D23.529.374.750.500
Unique ID
D008233
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D008233
Annotation
for "lymphocytotoxin" use CYTOTOXINS and LYMPHOCYTES
Scope Note
A tumor necrosis factor family member that is released by activated LYMPHOCYTES. Soluble lymphotoxin is specific for TUMOR NECROSIS FACTOR RECEPTOR TYPE I; TUMOR NECROSIS FACTOR RECEPTOR TYPE II; and TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 14. Lymphotoxin-alpha can form a membrane-bound heterodimer with LYMPHOTOXIN-BETA that has specificity for the LYMPHOTOXIN BETA RECEPTOR.
Entry Term(s)
Lymphotoxin
Lymphotoxin-alpha3
Soluble Lymphotoxin-alpha
TNF Superfamily, Member 1
TNF-beta
Tumor Necrosis Factor Ligand Superfamily Member 1
Tumor Necrosis Factor-beta
alpha-Lymphotoxin
Registry Numbers
0
Public MeSH Note
2007; was LYMPHOTOXIN 1990-2006; LYMPHOTOXIN-ALPHA was indexed under LYMPHOTOXIN see LYMPHOTOXINS 1978-1989; see LYMPHOTOXIN 1974-1977; for TUMOR NECROSIS FACTOR-BETA & TNF-BETA see TUMOR NECROSIS FACTOR 1988-1989
History Note
2007 (1974-1977); for TUMOR NECROSIS FACTOR-BETA & TNF-BETA use TUMOR NECROSIS FACTOR 1988-1989
Date Established
1974/01/01
Date of Entry
1999/01/01
Revision Date
2015/06/23
Lymphotoxin-alpha Preferred
Lymphotoxin-alpha3 Narrower
page delivered in 0.16s