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Mitogen-Activated Protein Kinases MeSH Descriptor Data 2022


MeSH Heading
Mitogen-Activated Protein Kinases
Tree Number(s)
D08.811.913.696.620.682.700.567
D12.776.476.563.567
Unique ID
D020928
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020928
Scope Note
A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Entry Term(s)
Mitogen Activated Protein Kinase
Mitogen-Activated Protein Kinase
Registry Number
EC 2.7.11.24
Previous Indexing
Ca(2+)-Calmodulin Dependent Protein Kinase (1994-1999)
Protein Kinases (1989-1999)
Protein-Serine-Threonine Kinases (1993-1999)
Protein-Tyrosine Kinase (1989-1999)
See Also
MAP Kinase Signaling System
Public MeSH Note
2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES see CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
History Note
2000; for EXTRACELLULAR SIGNAL-REGULATED KINASES use CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE 1994-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2021/07/12
Mitogen-Activated Protein Kinases Preferred
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