- Concept UI
- M000613481
- Scope Note
- A serine/threonine-protein kinase that functions in AUTOPHAGY in response to starvation. It acts on the PHOSPHATIDYLINOSITOL 3-KINASE complex PIK3C3 to regulate AUTOPHAGOSOME formation. It also functions as both a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) and is activated by AMPK, which it also negatively regulates.
- Terms
-
Autophagy-Related Protein-1 Homolog
Preferred Term
Term UI
T000893509
Date01/12/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
Serine-Threonine Protein Kinase ULK1
Term UI
T000893574
Date01/13/2016
LexicalTag
ABX
ThesaurusID
NLM (2017)
-
ULK1 Protein
Term UI
T000893510
Date01/12/2016
LexicalTag
ABX
ThesaurusID
NLM (2017)
-
Unc-51-Like Kinase 1
Term UI
T000893511
Date01/12/2016
LexicalTag
NON
ThesaurusID
NLM (2017)
-
Unc-51 Like Autophagy Activating Kinase 1
Term UI
T000893512
Date01/12/2016
LexicalTag
NON
ThesaurusID
NLM (2017)