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Autophagy-Related Protein 12 MeSH Descriptor Data 2022


MeSH Heading
Autophagy-Related Protein 12
Tree Number(s)
D12.776.094.391
D12.776.947.125
Unique ID
D000071192
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071192
Scope Note
A UBIQUITIN-like modifier protein that functions in AUTOPHAGOSOME formation, CYTOPLASM to VACUOLE transport, MITOPHAGY, and nucleophagy. Conjugation with ATG5 PROTEIN or ATG10 is essential for its function. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme for lipid modification of ATG8 FAMILY PROTEINS and their localization to vesicle membranes.
Entry Term(s)
ATG12 Protein
Ubiquitin-Like Protein ATG12
Registry Number
0
Previous Indexing
Small Ubiquitin-Related Modifier Proteins (2008-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/25
Autophagy-Related Protein 12 Preferred
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