MeSH Browser

MeSH Heading: Ubiquitin
Tree Number(s): D12.776.947.500
Unique ID: D025801
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D025801
Annotation: UBIQUITINS is also available
Scope Note: A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These ubiquitinated proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
Entry Term(s): APF-1; ATP-Dependent Proteolysis Factor 1; HMG-20; High Mobility Protein 20; Ubiquitin, Human
Registry Numbers: 0; 79586-22-4
Related Numbers: 79586-22-4
Previous Indexing: Chromosomal Proteins, Non-Histone (1977-1984); Nucleoproteins (1966-1977); Peptides (1975-1980); Ubiquitins (1985-2001)
Public MeSH Note: 2002; see UBIQUITINS (1985-2001)
History Note: 2002; use UBIQUITINS (1985-2001)
Date Introduced: 2002/01/01
Last Updated: 2015/06/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0369737
Registry Numbers: 0
Related Numbers: 79586-22-4
Scope Note: A highly conserved 76-amino acid peptide universally found in eukaryotic cells that functions as a marker for intracellular PROTEIN TRANSPORT and degradation. Ubiquitin becomes activated through a series of complicated steps and forms an isopeptide bond to lysine residues of specific proteins within the cell. These ubiquitinated proteins can be recognized and degraded by proteosomes or be transported to specific compartments within the cell.
Terms: Ubiquitin Preferred Term
Term UI T042285
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1985); APF-1
Term UI T042280
Date05/30/1984
LexicalTag ABB
ThesaurusID UNK (19XX); ATP-Dependent Proteolysis Factor 1
Term UI T042281
Date05/30/1984
LexicalTag NON
ThesaurusID UNK (19XX); High Mobility Protein 20
Term UI T042282
Date02/22/1993
LexicalTag NON
ThesaurusID NLM (1994); HMG-20
Term UI T042284
Date02/22/1993
LexicalTag ABB
ThesaurusID NLM (1994)

Ubiquitin MeSH Descriptor Data 2026