- Concept UI
- M000631126
- Registry Numbers
- 0
- Scope Note
- A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins
- Terms
-
NEDD8 Protein
Preferred Term
Term UI
T000923462
Date05/05/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)
-
NEDD-8 Protein
Term UI
T000923463
Date05/05/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)
-
Ubiquitin-like Protein NEDD8
Term UI
T000923464
Date05/05/2017
LexicalTag
ACX
ThesaurusID
NLM (2018)
-
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Term UI
T000923465
Date05/05/2017
LexicalTag
NON
ThesaurusID
NLM (2018)