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Autophagy-Related Protein 7 MeSH Descriptor Data 2022


MeSH Heading
Autophagy-Related Protein 7
Tree Number(s)
D12.776.094.399
Unique ID
D000071193
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071193
Scope Note
An autophagy related protein that is similar to UBIQUITIN-ACTIVATING ENZYME E1. It functions in CYTOPLASM to VACUOLE transport (Cvt) and AUTOPHAGY by activating ATG12 PROTEIN for its conjugation with ATG5 PROTEIN, as well as the conjugation of ATG8 FAMILY PROTEINS with phosphatidylethanolamine for ATG8 association to Cvt vesicles and AUTOPHAGOSOME membranes. It is also required for the nitrogen starvation response in yeast, MITOPHAGY; and autophagic cell death induced by CASPASE 8 inhibition.
Entry Term(s)
ATG12-Activating Enzyme E1 ATG7
ATG7 Protein
Ubiquitin-Activating Enzyme E1-like Protein
Ubiquitin-Like Modifier-Activating Enzyme ATG7
Registry Number
EC 6.2.1.45
Previous Indexing
Microtubule-Associated Proteins (2005-2016)
Ubiquitin-Activating Enzymes (2006-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/25
Autophagy-Related Protein 7 Preferred
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