MeSH Browser

MeSH Heading: Wnt Proteins
Tree Number(s): D12.776.467.984; D23.529.984
Unique ID: D051153
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051153
Scope Note: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
Entry Term(s): Wingless Type Protein; Wingless Type Proteins; Wnt Factor; Wnt Factors; Wnt Protein
Public MeSH Note: 2006; WNT PROTEINS was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2005, & under PROTO-ONCOGENE PROTEINS 1987-2005
History Note: 2006(1987)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0151350
Scope Note: Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
Terms: Wnt Proteins Preferred Term
Term UI T628086
Date01/17/2005
LexicalTag ABX
ThesaurusID NLM (2006); Wnt Protein
Term UI T000999232
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); Wingless Type Proteins
Term UI T628089
Date01/17/2005
LexicalTag NON
ThesaurusID NLM (2006); Wingless Type Protein
Term UI T000999233
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021); Wnt Factors
Term UI T628088
Date01/17/2005
LexicalTag ABX
ThesaurusID NLM (2006); Wnt Factor
Term UI T000999234
Date11/22/2019
LexicalTag NON
ThesaurusID NLM (2021)

Wnt Proteins MeSH Descriptor Data 2024