MeSH Browser

MeSH Heading: Endothelial Growth Factors
Tree Number(s): D12.644.276.390; D12.776.467.390; D23.529.390
Unique ID: D016228
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016228
Annotation: do not confuse with EGF; (EPIDERMAL GROWTH FACTOR)
Scope Note: These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
Entry Version: ECGF
Entry Term(s): ECDGF; Endo-GF; Endothelial Cell-Derived Growth Factors; Endothelial Growth Factor; Endothelial Growth Factor Polypeptides; alpha-Endothelial Growth Factor; beta-Endothelial Growth Factor
Pharm Action: Growth Substances
Registry Numbers: 0
Previous Indexing: Fibroblast Growth Factor (1984-1990); Growth Substances (1966-1983)
See Also: Vascular Endothelial Growth Factor A
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/30
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0024785
Registry Numbers: 0
Scope Note: These growth factors are soluble mitogens secreted by a variety of organs. The factors are a mixture of two single chain polypeptides which have affinity to heparin. Their molecular weight are organ and species dependent. They have mitogenic and chemotactic effects and can stimulate endothelial cells to grow and synthesize DNA. The factors are related to both the basic and acidic FIBROBLAST GROWTH FACTORS but have different amino acid sequences.
Terms: Endothelial Growth Factors Preferred Term
Term UI T048318
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1991); ECDGF
Term UI T048314
Date03/05/1990
LexicalTag ABB
ThesaurusID NLM (1991); Endo-GF
Term UI T048315
Date03/05/1990
LexicalTag ABB
ThesaurusID NLM (1991); Endothelial Cell-Derived Growth Factors
Term UI T048316
Date03/05/1990
LexicalTag NON
ThesaurusID NLM (1991); Endothelial Growth Factor
Term UI T048317
Date03/05/1990
LexicalTag NON
ThesaurusID NLM (1991); Endothelial Growth Factor Polypeptides
Term UI T618280
Date11/17/2004
LexicalTag NON
ThesaurusID NLM (2006)

Endothelial Growth Factors MeSH Descriptor Data 2025