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Endothelins MeSH Descriptor Data 2022


MeSH Heading
Endothelins
Tree Number(s)
D12.644.276.400
D12.776.467.400
D23.529.400
Unique ID
D016232
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016232
Annotation
general or unspecified; prefer specifics
Scope Note
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
Entry Term(s)
Endothelin
Endothelium-Derived Vasoconstrictor Factors
Registry Number
0
Previous Indexing
Peptides (1966-1990)
See Also
Receptors, Endothelin
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/06/28
Revision Date
2006/07/05
Endothelins Preferred
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