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E2F Transcription Factors MeSH Descriptor Data 2025


MeSH Heading
E2F Transcription Factors
Tree Number(s)
D12.776.930.211
Unique ID
D050684
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050684
Scope Note
A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.
Entry Term(s)
E2F Proteins
E2F Transcription Factor
Transcription Factor E2F
Registry Numbers
0
Previous Indexing
Cell Cycle Proteins (1991-2005)
DNA-Binding Proteins (1991-2005)
Transcription Factors (1991-2005)
Public MeSH Note
2006; E2F TRANSCRIPTION FACTORS was indexed under CELL CYCLE PROTEINS, DNA-BINDING PROTEINS, & TRANSCRIPTION FACTORS 1991-2005
History Note
2006(1991)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2020/05/27
E2F Transcription Factors Preferred
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