MeSH Browser

MeSH Heading: Homeobox Protein Nkx-2.5
Tree Number(s): D12.776.260.400.234; D12.776.930.324
Unique ID: D000072576
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072576
Scope Note: A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
Entry Term(s): Cardiac-Specific Homeobox Protein; Homeobox Protein Csx-Nkx2.5; Homeobox Transcription Factor Csx-Nkx2-5; NK2 Homeobox 5 Protein; Transcription Factor Nkx-2.5
Previous Indexing: Homeodomain Proteins (1995-2016); Transcription Factors (1995-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000617314
Scope Note: A homeobox-containing transcription factor that functions in heart development. Mutations in the NKX2-5 gene are associated with ATRIAL SEPTAL DEFECTS and TETRALOGY OF FALLOT.
Terms: Homeobox Protein Nkx-2.5 Preferred Term
Term UI T000900002
Date04/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); Cardiac-Specific Homeobox Protein
Term UI T000900003
Date04/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); Transcription Factor Nkx-2.5
Term UI T000900004
Date04/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); Homeobox Transcription Factor Csx-Nkx2-5
Term UI T000900005
Date04/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); Homeobox Protein Csx-Nkx2.5
Term UI T000900006
Date04/28/2016
LexicalTag ABX
ThesaurusID NLM (2017); NK2 Homeobox 5 Protein
Term UI T000902566
Date06/10/2016
LexicalTag ABX
ThesaurusID NLM (2017)

Homeobox Protein Nkx-2.5 MeSH Descriptor Data 2024