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Zinc Finger E-box Binding Homeobox 2 MeSH Descriptor Data 2022


MeSH Heading
Zinc Finger E-box Binding Homeobox 2
Tree Number(s)
D12.776.260.400.883
D12.776.260.703.700
D12.776.930.780.918
Unique ID
D000074165
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074165
Scope Note
A transcription factor that consists of 8 CYS2-HIS2 ZINC FINGERS flanking a central HOMEOBOX. It binds to the 5'-CACCT-3' DNA sequence located within E-BOX ELEMENTS of many genes essential for embryonic growth and development and regulates their activity; it represses transcription of the E-CADHERIN gene. Mutations in the ZEB2 gene are associated with MOWAT-WILSON SYNDROME.
Entry Term(s)
Smad-Interacting Protein 1
Zeb2 Transcription Factor
Zinc Finger E-box Binding Homeobox 2 Protein
Registry Number
0
Previous Indexing
Homeodomain Proteins (2004-2017)
Repressor Proteins (2004-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/02/27
Zinc Finger E-box Binding Homeobox 2 Preferred
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