- Concept UI
- M0232680
- Registry Numbers
- EC 2.3.1.48
- Scope Note
- A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
- Terms
-
p300-CBP Transcription Factors
Preferred Term
Term UI
T627362
Date01/10/2005
LexicalTag
ABX
ThesaurusID
NLM (2006)
-
p300-CBP Coactivator
Term UI
T422087
Date08/18/2000
LexicalTag
ACX
ThesaurusID
NLM (2006)
-
p300-CBP Protein
Term UI
T625528
Date12/22/2004
LexicalTag
ABX
ThesaurusID
NLM (2006)