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bcl-2-Associated X Protein MeSH Descriptor Data 2025
Don't confuse with the closely related BCL-X PROTEIN
Scope Note
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.
Entry Term(s)
Bax Apoptosis Regulator Protein
Bax Protein
Bax-alpha Protein
Bax-beta Protein
Bax-delta Protein
Bax-omega Protein
Bax-sigma Protein
bcl2-Associated X Protein
bcl2-Associated X Protein Isoform alpha
bcl2-Associated X Protein Isoform beta
bcl2-Associated X Protein Isoform delta
bcl2-Associated X Protein Isoform omega
bcl2-Associated X Protein Isoform sigma
Registry Numbers
0
Public MeSH Note
2006; BCL2-ASSOCIATED X-PROTEIN was indexed under PROTO-ONCOGENE PROTEINS C-BCL-2 1993-2005
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS INDUCING FACTOR from the MITOCHONDRIA. Several isoforms of BCL2-associated X protein occur due to ALTERNATIVE SPLICING of the mRNA for this protein.