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Genes, bcl-2 MeSH Descriptor Data 2023


MeSH Heading
Genes, bcl-2
Tree Number(s)
G05.360.340.024.340.375.500.791.150
Unique ID
D019254
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019254
Annotation
bcl stands for "B-Cell Leukemia"
Scope Note
The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.
Entry Term(s)
bcl-2 Genes
c-bcl-2 Genes
c-bcl-2 Proto-Oncogenes
Previous Indexing
Oncogenes (1984-1996)
Proto-Oncogenes (1988-1996)
See Also
Proto-Oncogene Proteins c-bcl-2
Public MeSH Note
97
History Note
97
Date Established
1997/01/01
Date of Entry
1996/06/13
Revision Date
2008/07/08
Genes, bcl-2 Preferred
c-bcl-2 Genes Narrower
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