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Genes, erbB MeSH Descriptor Data 2022


MeSH Heading
Genes, erbB
Tree Number(s)
G05.360.340.024.340.375.500.791.295
Unique ID
D018815
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018815
Annotation
spell in titles & translations as erbB; GENES, ERBB-1 & GENES, ERBB-2 are also available
Scope Note
Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
Entry Term(s)
c-erbB-3 Genes
erbB Genes
erbB-3 Genes
Previous Indexing
Proto-Oncogenes (1992-1994)
Public MeSH Note
95
History Note
95
Date Established
1995/01/01
Date of Entry
1994/05/23
Revision Date
2008/07/08
Genes, erbB Preferred
c-erbB-3 Genes Narrower
erbB-3 Genes Narrower
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