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Genes, fos MeSH Descriptor Data 2022


MeSH Heading
Genes, fos
Tree Number(s)
G05.360.340.024.340.375.500.791.330
Unique ID
D016762
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016762
Annotation
fos stands for "Finkel" & "Osteogenic Sarcoma"
Scope Note
Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
Entry Term(s)
c-fos Genes
c-fos Proto-Oncogenes
fos Genes
v-fos Genes
v-fos Oncogenes
Previous Indexing
Oncogenes (1983-1991)
Proto-Oncogenes (1985-1991)
See Also
Oncogene Proteins v-fos
Proto-Oncogene Proteins c-fos
Public MeSH Note
92
History Note
92
Date Established
1992/01/01
Date of Entry
1991/07/12
Revision Date
2008/07/08
Genes, fos Preferred
c-fos Genes Narrower
v-fos Genes Narrower
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