MeSH Browser

MeSH Heading: Genes, fos
Tree Number(s): G05.360.340.024.340.375.500.791.330
Unique ID: D016762
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016762
Annotation: fos stands for "Finkel" & "Osteogenic Sarcoma"
Scope Note: Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
Entry Term(s): c-fos Genes; c-fos Proto-Oncogenes; fos Genes; v-fos Genes; v-fos Oncogenes
Previous Indexing: Oncogenes (1983-1991); Proto-Oncogenes (1985-1991)
See Also: Oncogene Proteins v-fos; Proto-Oncogene Proteins c-fos
Public MeSH Note: 92
History Note: 92
Date Established: 1992/01/01
Date of Entry: 1991/07/12
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Genes, fos MeSH Descriptor Data 2024