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Genes, erbA MeSH Descriptor Data 2023


MeSH Heading
Genes, erbA
Tree Number(s)
G05.360.340.024.340.375.500.791.290
Unique ID
D018776
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018776
Annotation
erbA stands for "ERythroBlastosis virus, Avian"; GENES, ERBB & its specifics are also available; in titles & translations spell as erbA
Scope Note
Genes related to the erbA DNA sequence that was first isolated from the avian erythroblastosis virus (ERYTHROBLASTOSIS VIRUS, AVIAN), v-erbA. In cells, erbA genes encode thyroid hormone receptors (RECEPTORS, THYROID HORMONE). Two distinct c-erbA genes have been identified: erbA-alpha located at 17q21; and erbA-beta located at 3p24. Truncations at the N- and C-terminals of erbA result in products resembling v-erbA. Truncations affect hormone responsiveness but not DNA binding capacity.
Entry Term(s)
Genes, THRA
Genes, THRB
Genes, TR alpha
Genes, TR beta
Genes, TR-alpha
Genes, TR-beta
Genes, erbA alpha
Genes, erbA beta
Genes, erbA-alpha
Genes, erbA-beta
c-erbA Genes
c-erbA Proto-Oncogenes
erbA Genes
v-erbA Genes
v-erbA Oncogenes
Previous Indexing
Oncogenes (1984-1994)
Proto-Oncogenes (1987-1994)
See Also
Oncogene Proteins v-erbA
Receptors, Thyroid Hormone
Public MeSH Note
95
History Note
95
Date Established
1995/01/01
Date of Entry
1994/05/23
Revision Date
2008/07/08
Genes, erbA Preferred
Genes, erbA-beta Narrower
Genes, erbA-alpha Narrower
v-erbA Genes Narrower
c-erbA Genes Narrower
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