MeSH Browser

MeSH Heading: Genes, myb
Tree Number(s): G05.360.340.024.340.375.500.791.418
Unique ID: D020570
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020570
Scope Note: Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
Entry Term(s): c-myb Genes; c-myb Proto-Oncogenes; myb Genes; myb Oncogene; v-myb Genes; v-myb Oncogenes
Previous Indexing: Genes, Viral (1983-1999); Oncogenes (1983-1999)
Public MeSH Note: 2000; use ONCOGENES 1985-1999
History Note: 2000; use ONCOGENES 1985-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Genes, myb MeSH Descriptor Data 2024