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Genes, myb MeSH Descriptor Data 2023


MeSH Heading
Genes, myb
Tree Number(s)
G05.360.340.024.340.375.500.791.418
Unique ID
D020570
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020570
Scope Note
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
Entry Term(s)
c-myb Genes
c-myb Proto-Oncogenes
myb Genes
myb Oncogene
v-myb Genes
v-myb Oncogenes
Previous Indexing
Genes, Viral (1983-1999)
Oncogenes (1983-1999)
Public MeSH Note
2000; use ONCOGENES 1985-1999
History Note
2000; use ONCOGENES 1985-1999
Date Established
2000/01/01
Date of Entry
1999/11/03
Revision Date
2008/07/08
Genes, myb Preferred
v-myb Genes Narrower
c-myb Genes Narrower
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