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Genes, myc MeSH Descriptor Data 2022


MeSH Heading
Genes, myc
Tree Number(s)
G05.360.340.024.340.375.500.791.420
Unique ID
D016259
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016259
Annotation
myc stands for "MYeloCytomatosis"
Scope Note
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
Entry Term(s)
L-myc Genes
L-myc Proto-Oncogenes
N-myc Genes
N-myc Proto-Oncogenes
c-myc Genes
c-myc Proto-Oncogenes
myc Genes
myc Oncogene
v-myc Genes
v-myc Oncogenes
Previous Indexing
Genes, Viral (1982)
Oncogenes (1983-1990)
See Also
Oncogene Protein p55(v-myc)
Proto-Oncogene Proteins c-myc
Public MeSH Note
91; was MYC GENES see ONCOGENES 1985-90
Online Note
use ONCOGENES to search MYC GENES 1985-90
History Note
91; was MYC GENES see ONCOGENES 1985-90
Date Established
1991/01/01
Date of Entry
1990/06/28
Revision Date
2008/07/08
Genes, myc Preferred
c-myc Genes Narrower
c-myc Proto-Oncogenes Narrower
v-myc Genes Narrower
L-myc Proto-Oncogenes Narrower
myc Oncogene Narrower
N-myc Genes Narrower
N-myc Proto-Oncogenes Narrower
v-myc Oncogenes Narrower
L-myc Genes Narrower
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