- Concept UI
- M0073416
- Registry Numbers
- EC 4.2.99.18
- Scope Note
- A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2.
- Terms
-
DNA-(Apurinic or Apyrimidinic Site) Lyase
Preferred Term
Term UI
T103419
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2004)
-
DNA Lyase (Apurinic or Apyrimidinic)
Term UI
T544320
Date06/25/2003
LexicalTag
NON
ThesaurusID
NLM (2004)
-
AP Endonuclease
Term UI
T103400
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2004)
-
AP Lyase
Term UI
T103401
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2004)
-
Apurine-Apyrimidine Endonuclease
Term UI
T103409
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)
-
Apurinic DNA Endonuclease
Term UI
T103410
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2004)
-
Apurinic Endonuclease
Term UI
T103411
Date01/01/1955
LexicalTag
ABX
ThesaurusID
NLM (2004)
-
Endodeoxyribonuclease (Apurinic or Apyrimidinic)
Term UI
T103413
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2004)