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DNA Helicases MeSH Descriptor Data 2022


MeSH Heading
DNA Helicases
Tree Number(s)
D08.811.277.040.025.159
D08.811.399.340
Unique ID
D004265
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004265
Annotation
do not confuse entry term DNA UNWINDING PROTEINS with DNA UNTWISTING PROTEINS
Scope Note
Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition, DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.
Entry Term(s)
ATP-Dependent DNA Helicase
ATP-Dependent DNA Helicases
DNA Helicase
DNA Helicase A
DNA Helicase E
DNA Helicase II
DNA Helicase III
DNA Unwinding Protein
DNA Unwinding Proteins
Registry Number
EC 3.6.4.-
Related Numbers
EC 3.6.4.12
NLM Classification #
QU 137
Previous Indexing
Deoxyribonucleases (1966-1977)
Endonucleases (1973-1977)
Proteins (1966-1977)
specific protein (1966-1977)
Public MeSH Note
1994; see DNA UNWINDING PROTEINS 1978-1993; for DNA HELICASE A, DNA HELICASE E, DNA HELICASE II were indexed under ADENOSINE TRIPHOSPHATASES & DNA HELICASES 1980-2006; DNA HELICASE III was indexed under DNA HELICASES 1981-2006 & under DNA GYRASE 1980-1981, & under DNA, SUPERHELICAL 1979-1980
History Note
1994
Date Established
1978/01/01
Date of Entry
1977/04/15
Revision Date
2021/06/30
DNA Helicases Preferred
DNA Helicase III Narrower
DNA Helicase E Narrower
DNA Helicase II Narrower
ATP-Dependent DNA Helicases Narrower
DNA Helicase A Narrower
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