NLM Logo

RecQ Helicases MeSH Descriptor Data 2022


MeSH Heading
RecQ Helicases
Tree Number(s)
D08.811.277.040.025.159.249
D08.811.399.340.249
Unique ID
D053484
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053484
Scope Note
A family of structurally-related DNA helicases that play an essential role in the maintenance of genome integrity. RecQ helicases were originally discovered in E COLI and are highly conserved across both prokaryotic and eukaryotic organisms. Genetic mutations that result in loss of RecQ helicase activity gives rise to disorders that are associated with CANCER predisposition and premature aging.
Entry Term(s)
ATP-Dependent DNA Helicase Q1
ATP-Dependent DNA Helicase Q4
ATP-Dependent DNA Helicase Q5
DNA Helicase Q1
DNA Helicase RecQL
DNA Helicase RecQL4
DNA Helicase, RecQ-like type 2
DNA-Dependent ATPase Q1
RECQL1 Helicase
RTS Helicase
RecQ Family of DNA Helicase
RecQ Family of DNA Helicases
RecQ Helicase
RecQ Protein
RecQ2 Helicase
RecQ3 Helicase
RecQ4 Helicase
RecQ5 Helicase
RecQ5L Helicase
RecQL Helicase
RecQL2 Helicase
RecQL3 Helicase
RecQL4 Helicase
Registry Number
EC 3.6.4.12
Related Numbers
EC 3.6.4.12
See Also
Bloom Syndrome
Rothmund-Thomson Syndrome
Werner Syndrome
Public MeSH Note
2007: RECQ HELICASES was indexed under ADENOSINE TRIPHOSPHATASES & DNA HELICASES 1990-2006; RECQ4 HELICASE was indexed under DNA HELICASES 2002-2006; DNA HELICASE RECQL was indexed under DNA HELICASES & ADENOSINE TRIPHOSPHATASES 1994-2006; RECQ5 HELICASE was indexed under DNA HELICASES 1999-2006
History Note
2007(1990)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2020/05/27
RecQ Helicases Preferred
RecQL Helicase Narrower
RecQ4 Helicase Narrower
RecQ5 Helicase Narrower
RecQ2 Helicase Narrower
RecQ3 Helicase Narrower
page delivered in 0.142s