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Polyendocrinopathies, Autoimmune MeSH Descriptor Data 2022


MeSH Heading
Polyendocrinopathies, Autoimmune
Tree Number(s)
C19.787
C20.111.750
Unique ID
D016884
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016884
Annotation
do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed
Scope Note
Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
Entry Term(s)
AIRE Deficiency
APECED
APS Type 1
Autoimmune Polyendocrine Syndrome, Type 2
Autoimmune Polyendocrine Syndrome, Type II
Autoimmune Polyendocrinopathy Syndrome Type 1
Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy
Autoimmune Polyglandular Syndrome Type I
Autoimmune Polyglandular Syndrome Type II
Autoimmune Polyglandular Syndrome Type III
Autoimmune Polyglandular Syndrome, Type 1
Autoimmune Polyglandular Syndrome, Type 3
Autoimmune Polyglandular Syndrome, Type I
Autoimmune Syndrome Type I, Polyglandular
Autoimmune Syndrome Type II, Polyglandular
Autoimmune Syndrome Type III, Polyglandular
Diabetes Mellitus, Addison Disease, Myxedema
Diabetes Mellitus, Addison's Disease, Myxedema
Multiple Endocrine Deficiency Syndrome, Type 2
Polyendocrine Autoimmune Syndrome, Type II
Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune
Polyglandular Autoimmune Syndrome, Type 1
Polyglandular Autoimmune Syndrome, Type 2
Polyglandular Autoimmune Syndrome, Type 3
Polyglandular Autoimmune Syndrome, Type I
Polyglandular Deficiency Syndrome, Type 2
Polyglandular Type I Autoimmune Syndrome
Polyglandular Type II Autoimmune Syndrome
Polyglandular Type III Autoimmune Syndrome
Schmidt Syndrome
Schmidt's Syndrome
NLM Classification #
WK 140
Previous Indexing
Autoimmune Diseases (1968-1991)
Endocrine Diseases (1978-1991)
Public MeSH Note
1992
History Note
1992
Date Established
1992/01/01
Date of Entry
1991/05/02
Revision Date
2013/07/08
Polyendocrinopathies, Autoimmune Preferred
Polyglandular Type III Autoimmune Syndrome Narrower
Polyglandular Type I Autoimmune Syndrome Narrower
Polyglandular Type II Autoimmune Syndrome Narrower
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