MeSH Browser

MeSH Heading: Polyendocrinopathies, Autoimmune
Tree Number(s): C19.787; C20.111.750
Unique ID: D016884
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016884
Annotation: do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed
Scope Note: Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.
Entry Term(s): AIRE Deficiency; APECED; APS Type 1; Autoimmune Polyendocrine Syndrome, Type 2; Autoimmune Polyendocrine Syndrome, Type II; Autoimmune Polyendocrinopathy Syndrome Type 1; Autoimmune Polyendocrinopathy with Candidiasis and Ectodermal Dystrophy; Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy; Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy; Autoimmune Polyglandular Syndrome Type I; Autoimmune Polyglandular Syndrome Type II; Autoimmune Polyglandular Syndrome Type III; Autoimmune Polyglandular Syndrome, Type 1; Autoimmune Polyglandular Syndrome, Type 3; Autoimmune Polyglandular Syndrome, Type I; Autoimmune Syndrome Type I, Polyglandular; Autoimmune Syndrome Type II, Polyglandular; Autoimmune Syndrome Type III, Polyglandular; Diabetes Mellitus, Addison Disease, Myxedema; Diabetes Mellitus, Addison's Disease, Myxedema; Multiple Endocrine Deficiency Syndrome, Type 2; Polyendocrine Autoimmune Syndrome, Type II; Polyendocrinopathy-Candidiasis-Ectodermal-Dystrophy, Autoimmune; Polyglandular Autoimmune Syndrome, Type 1; Polyglandular Autoimmune Syndrome, Type 2; Polyglandular Autoimmune Syndrome, Type 3; Polyglandular Autoimmune Syndrome, Type I; Polyglandular Deficiency Syndrome, Type 2; Polyglandular Type I Autoimmune Syndrome; Polyglandular Type II Autoimmune Syndrome; Polyglandular Type III Autoimmune Syndrome; Schmidt Syndrome; Schmidt's Syndrome
NLM Classification #: WK 140
Previous Indexing: Autoimmune Diseases (1968-1991); Endocrine Diseases (1978-1991)
Public MeSH Note: 1992
History Note: 1992
Date Established: 1992/01/01
Date of Entry: 1991/05/02
Revision Date: 2013/07/08

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Endocrine System Diseases [C19]

Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]

Polyendocrinopathies, Autoimmune Preferred

Polyglandular Type I Autoimmune Syndrome Narrower

Polyglandular Type II Autoimmune Syndrome Narrower

Polyglandular Type III Autoimmune Syndrome Narrower

Polyendocrinopathies, Autoimmune MeSH Descriptor Data 2024