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Purpura, Thrombocytopenic, Idiopathic MeSH Descriptor Data 2025
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
Entry Term(s)
Autoimmune Thrombocytopenia
Autoimmune Thrombocytopenic Purpura
Idiopathic Thrombocytopenic Purpura
Immune Thrombocytopenia
Immune Thrombocytopenic Purpura
Purpura, Thrombocytopenic, Autoimmune
Thrombocytopenic Purpura, Autoimmune
Werlhof Disease
Werlhof's Disease
NLM Classification #
WH 322
Previous Indexing
Purpura, Thrombocytopenic (1966-1991)
Public MeSH Note
1992; for WERLHOF'S DISEASE see PURPURA, THROMBOCYTOPENIC 1975-1991
History Note
1992; for WERLHOF'S DISEASE use PURPURA, THROMBOCYTOPENIC 1975-1991
Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.