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Hemophilia B MeSH Descriptor Data 2024


MeSH Heading
Hemophilia B
Tree Number(s)
C15.378.100.100.510
C15.378.100.141.510
C15.378.463.510
C16.320.099.510
C16.320.322.235
Unique ID
D002836
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D002836
Scope Note
A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008)
Entry Term(s)
Christmas Disease
Deficiency, Factor IX
F9 Deficiency
Factor IX Deficiency
Haemophilia B
Hemophilia B Leyden
Hemophilia B(M)
Plasma Thromboplastin Component Deficiency
NLM Classification #
WH 325
See Also
Hemophilia A
Public MeSH Note
1999; see CHRISTMAS DISEASE 1966-1998; for HEMOPHILIA B see CHRISTMAS DISEASE 1974-1998; for Hemophilia B Leyden see FACTOR IX 1990-2012
History Note
1999(1966)
Date Established
1999/01/01
Date of Entry
1999/01/01
Revision Date
2016/06/28
Hemophilia B Preferred
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