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Activated Protein C Resistance MeSH Descriptor Data 2025


MeSH Heading
Activated Protein C Resistance
Tree Number(s)
C15.378.100.100.037
C15.378.100.141.036
C15.378.925.050
C16.320.099.037
Unique ID
D020016
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020016
Scope Note
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
Entry Term(s)
APC Resistance
Previous Indexing
Factor V/genetics (1994-1998)
Protein C (1993-1998)
See Also
Protein C Deficiency
Public MeSH Note
1999
History Note
1999
Date Established
1999/01/01
Date of Entry
2024/08/09
Revision Date
2024/05/22
Activated Protein C Resistance Preferred
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