Pactamycin MeSH Descriptor Data 2024

MeSH Heading: Pactamycin
Tree Number(s): D02.241.223.100.300.450; D02.241.511.390.450; D02.455.426.559.389.127.281.450; D02.455.426.559.389.657.410.450
Unique ID: D010142
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010142
Scope Note: Antibiotic produced by Streptomyces pactum used as an antineoplastic agent. It is also used as a tool in biochemistry because it inhibits certain steps in protein synthesis.
Pharm Action: Antibiotics, Antineoplastic
Protein Synthesis Inhibitors
Registry Number: 23668-11-3
CAS Type 1 Name: Benzoic acid, 2-hydroxy-6-methyl-, (5-((3-acetylphenyl)amino)-4-amino-3-(((dimethylamino)carbonyl)amino)-1,2-dihydroxy-3-(1-hydroxyethyl)-2-methylcyclopentyl)methyl ester, (1S-(1alpha,2beta,3alpha,3(R*),4alpha,5beta))-
Previous Indexing: Antibiotics, Antineoplastic (1972-1974)
Public MeSH Note: 91; was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
History Note: 91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Acids, Carbocyclic [D02.241.223]
    - Benzoates [D02.241.223.100]
      - Hydroxybenzoates [D02.241.223.100.300]
        
        Depsides [D02.241.223.100.300.100]
        
        Gallic Acid [D02.241.223.100.300.200]
        
        3-Hydroxyanthranilic Acid [D02.241.223.100.300.300]
        
        Hydroxybenzoate Ethers [D02.241.223.100.300.350]
        
        Hydroxymercuribenzoates [D02.241.223.100.300.400]
        
        Pactamycin [D02.241.223.100.300.450]
        
        Parabens [D02.241.223.100.300.460]
        
        Salicylates [D02.241.223.100.300.595]

Organic Chemicals [D02]
- Carboxylic Acids [D02.241]
  - Hydroxy Acids [D02.241.511]
    - Hydroxybenzoates [D02.241.511.390]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Benzoates [D02.455.426.559.389.127]
        
        Hydroxybenzoates [D02.455.426.559.389.127.281]
        
        Depsides [D02.455.426.559.389.127.281.100]
        
        Gallic Acid [D02.455.426.559.389.127.281.200]
        
        Hydroxybenzoate Ethers [D02.455.426.559.389.127.281.350]
        
        Hydroxymercuribenzoates [D02.455.426.559.389.127.281.400]
        
        Pactamycin [D02.455.426.559.389.127.281.450]
        
        Parabens [D02.455.426.559.389.127.281.460]
        
        Salicylates [D02.455.426.559.389.127.281.595]

Organic Chemicals [D02]
- Hydrocarbons [D02.455]
  - Hydrocarbons, Cyclic [D02.455.426]
    - Hydrocarbons, Aromatic [D02.455.426.559]
      - Benzene Derivatives [D02.455.426.559.389]
        
        Phenols [D02.455.426.559.389.657]
        
        Hydroxybenzoates [D02.455.426.559.389.657.410]
        
        Depsides [D02.455.426.559.389.657.410.100]
        
        Gallic Acid [D02.455.426.559.389.657.410.200]
        
        Hydroxymercuribenzoates [D02.455.426.559.389.657.410.400]
        
        Pactamycin [D02.455.426.559.389.657.410.450]
        
        Parabens [D02.455.426.559.389.657.410.460]
        
        Salicylates [D02.455.426.559.389.657.410.595]

Pactamycin Preferred

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