MeSH Browser

MeSH Heading: Pentylenetetrazole
Tree Number(s): D03.383.066.600
Unique ID: D010433
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D010433
Scope Note: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
Entry Term(s): Cardiazol; Corasol; Corazol; Corazole; Korazol; Korazole; Leptazole; Metrazol; Metrazole; Pentamethylenetetrazole; Pentazol; Pentetrazole; Pentylenetetrazol
Pharm Action: Convulsants
GABA Antagonists
Related Numbers: 54-95-5
CAS Type 1 Name: 5H-Tetrazolo(1,5-a)azepine, 6,7,8,9-tetrahydro-
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0016203
Related Numbers: 54-95-5
Scope Note: A pharmaceutical agent that displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GAMMA-AMINOBUTYRIC ACID antagonist. Pentylenetetrazole has been used experimentally to study seizure phenomenon and to identify pharmaceuticals that may control seizure susceptibility.
Terms: Pentylenetetrazole Preferred Term
Term UI T030835
Date01/01/1999
LexicalTag NON
ThesaurusID; Leptazole
Term UI T030830
Date03/30/1974
LexicalTag NON
ThesaurusID UNK (19XX); Pentamethylenetetrazole
Term UI T030832
Date04/29/1977
LexicalTag NON
ThesaurusID; Pentetrazole
Term UI T030834
Date04/29/1977
LexicalTag NON
ThesaurusID; Pentylenetetrazol
Term UI T030841
Date12/18/1981
LexicalTag NON
ThesaurusID

Concept UI: M0373141
Terms: Corasol Preferred Term
Term UI T030837
Date08/01/1980
LexicalTag TRD
ThesaurusID UNK (19XX); Corazol
Term UI T030838
Date08/01/1980
LexicalTag TRD
ThesaurusID UNK (19XX); Corazole
Term UI T030839
Date08/01/1980
LexicalTag TRD
ThesaurusID UNK (19XX); Korazol
Term UI T030840
Date08/01/1980
LexicalTag TRD
ThesaurusID UNK (19XX); Korazole
Term UI T030829
Date08/01/1980
LexicalTag TRD
ThesaurusID UNK (19XX)

Pentylenetetrazole MeSH Descriptor Data 2024