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Viral Plaque Assay MeSH Descriptor Data 2022


MeSH Heading
Viral Plaque Assay
Tree Number(s)
E01.370.225.875.970.790
E05.200.875.970.790
Unique ID
D010948
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D010948
Annotation
for viruses; coord IM or NIM with specific virus /‌growth (IM); do not confuse with HEMOLYTIC PLAQUE TECHNIQUE in immunol
Scope Note
Method for measuring viral infectivity and multiplication in CULTURED CELLS. Clear lysed areas or plaques develop as the VIRAL PARTICLES are released from the infected cells during incubation. With some VIRUSES, the cells are killed by a cytopathic effect; with others, the infected cells are not killed but can be detected by their hemadsorptive ability. Sometimes the plaque cells contain VIRAL ANTIGENS which can be measured by IMMUNOFLUORESCENCE.
Entry Term(s)
Bacteriophage Plaque Assay
Previous Indexing
Virus Cultivation (1966-1972)
Public MeSH Note
2012; see PLAQUE ASSAY 1973-2011
History Note
2012 (1973)
Date Established
1973/01/01
Date of Entry
1999/01/01
Revision Date
2011/06/24
Viral Plaque Assay Preferred
Bacteriophage Plaque Assay Narrower
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