MeSH Browser

MeSH Heading: RNA Polymerase II
Tree Number(s): D08.811.913.696.445.735.270.762
Unique ID: D012319
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D012319
Scope Note: A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
Entry Term(s): DNA-Dependent RNA Polymerase II; RNA Pol II; RNA Polymerase B
Previous Indexing: RNA Nucleotidyltransferases (1968-1972); RNA Polymerases (1973-1976)
Public MeSH Note: 84; was see under RNA POLYMERASES 1977-83
History Note: 84(77); was see under RNA POLYMERASES 1977-83
Date Established: 1984/01/01
Date of Entry: 1976/04/19
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0019146
Scope Note: A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. EC 2.7.7.6.
Terms: RNA Polymerase II Preferred Term
Term UI T036567
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1977); DNA-Dependent RNA Polymerase II
Term UI T036565
Date04/16/1976
LexicalTag NON
ThesaurusID UNK (19XX); RNA Polymerase B
Term UI T036566
Date12/09/1981
LexicalTag NON
ThesaurusID UNK (19XX); RNA Pol II
Term UI T840528
Date04/16/2013
LexicalTag ABB
ThesaurusID NLM (2014)

RNA Polymerase II MeSH Descriptor Data 2024