MeSH Browser

MeSH Heading: Sparteine
Tree Number(s): D03.132.722.750
Unique ID: D013034
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D013034
Scope Note: A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.
Entry Term(s): 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-; D-sparteine; Depasan Retard; Genisteine Alkaloid; L-Sparteine; Lupinidin; Lupinidine; Pachycarpine; Pachycarpine Sulfate (1:1), Pentahydrate, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Sulfate; Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer; Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine Sulfate Anhydrous; Sparteine, (+)-Isomer; Sparteine, (-)-Isomer; Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer; Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer; Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer; Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer; alpha-Isosparteine; beta-Isosparteine
Pharm Action: Anti-Arrhythmia Agents
Oxytocics
Registry Number: 298897D62S
Related Numbers: 14703-10-7; 24915-04-6; 299-39-8; 3599-17-5; 3D76XVF9R0; 42808-46-8; 446-95-7; 492-06-8; 492-08-0; 51799-26-9; 52670-59-4; 6160-12-9; 72198-25-5; 90-39-1; GQ3J2TLZ7E
Public MeSH Note: 1963; PACHYCARPINE was indexed under SPARTEINE 1973-2001
History Note: 1963; for PACHYCARPINE use SPARTEINE(NM) 1973-2001
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2022/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Alkaloids [D03.132]
  - Quinolizidine Alkaloids [D03.132.722]
    - Matrines [D03.132.722.500]
    - Sparteine [D03.132.722.750]

Sparteine Preferred

Concept UI: M0020199
Registry Number: 298897D62S
Related Numbers: 14703-10-7; 24915-04-6; 299-39-8; 3599-17-5; 3D76XVF9R0; 42808-46-8; 446-95-7; 492-06-8; 492-08-0; 51799-26-9; 52670-59-4; 6160-12-9; 72198-25-5; 90-39-1; GQ3J2TLZ7E
Scope Note: A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.
Terms: Sparteine Preferred Term
Term UI T038401
Date01/01/1999
LexicalTag NON
ThesaurusID; Sparteine, (-)-Isomer
Term UI T428154
Date11/06/2000
LexicalTag NON
ThesaurusID NLM (2002); L-Sparteine
Term UI T428167
Date11/06/2000
LexicalTag NON
ThesaurusID NLM (2002); 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-
Term UI T001118882
Date03/17/2022
LexicalTag NON
ThesaurusID NLM (2023); Lupinidin
Term UI T001118884
Date03/17/2022
LexicalTag NON
ThesaurusID NLM (2023); Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Term UI T451316
Date06/18/2001
LexicalTag NON
ThesaurusID NLM (2002); Lupinidine
Term UI T001118883
Date03/17/2022
LexicalTag NON
ThesaurusID NLM (2023)

Sparteine Sulfate Narrower

Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Related

Concept UI: M0045265
Registry Number: 492-08-0
Terms: Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Preferred Term
Term UI T428169
Date11/06/2000
LexicalTag NON
ThesaurusID NLM (2002); Pachycarpine
Term UI T075268
LexicalTag NON
ThesaurusID NLM (2002); D-sparteine
Term UI T075267
LexicalTag NON
ThesaurusID NLM (2002); Sparteine, (+)-Isomer
Term UI T428155
Date11/06/2000
LexicalTag NON
ThesaurusID NLM (2002)

Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer Narrower

Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer Related

Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer Related

Sparteine Sulfate Anhydrous Narrower

Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Depasan Retard Narrower

Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer Narrower

Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer Narrower

Sparteine MeSH Descriptor Data 2024