MeSH Browser

MeSH Heading: Trifluridine
Tree Number(s): D03.383.742.680.705.900; D13.570.230.855.900; D13.570.685.705.900
Unique ID: D014271
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D014271
Scope Note: An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
Entry Term(s): 2'-deoxy-5-(trifluoromethyl)uridine; 5-Trifluoromethyl-2'-deoxyuridine; TFT Ophtiole; Triflumann; Trifluoridine; Trifluorothymidine; Viromidin; Virophta; Viroptic
Pharm Action: Antimetabolites
Antiviral Agents
Related Numbers: 70-00-8
CAS Type 1 Name: Thymidine, alpha,alpha,alpha-trifluoro-
Previous Indexing: Fluorine (1972-1974); Thymidine (1972-1974)
Public MeSH Note: 1974; see TRIFLUOROTHYMIDINE 1975-1991, see THYMIDINE 1975-1990, 2'-DEOXY-5-(TRIFLUOROMETHYL)URIDINE was indexed under DEOXYURIDINE
History Note: 1974(1992)
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0021960
Related Numbers: 70-00-8
Scope Note: An antiviral derivative of THYMIDINE used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to HERPES SIMPLEX virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)
Terms: Trifluridine Preferred Term
Term UI T041780
Date01/01/1999
LexicalTag NON
ThesaurusID; 5-Trifluoromethyl-2'-deoxyuridine
Term UI T041778
Date02/04/1982
LexicalTag NON
ThesaurusID; Trifluorothymidine
Term UI T041779
Date10/29/1990
LexicalTag NON
ThesaurusID; Trifluoridine
Term UI T041782
Date10/01/1990
LexicalTag NON
ThesaurusID NLM (1992); 2'-deoxy-5-(trifluoromethyl)uridine
Term UI T484284
Date03/03/2002
LexicalTag NON
ThesaurusID

Trifluridine MeSH Descriptor Data 2024