MeSH Browser

MeSH Heading: 2-Acetylaminofluorene
Tree Number(s): D02.065.064.150; D02.241.081.018.110.080; D02.455.426.559.847.389.050; D04.615.389.050
Unique ID: D015073
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015073
Scope Note: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Entry Term(s): 2-AAF; 2-Acetamidofluorene; 2-Fluorenylacetamide; AAF, Aminofluorene; Acetylaminofluorene; Fluoren-2-ylacetamide; N-2-Fluorenylacetamide; N-Acetyl-2-Aminofluorene
Pharm Action: Carcinogens
Registry Number: 9M98QLJ2DL
Related Numbers: 53-96-3
CAS Type 1 Name: Acetamide, N-9H-fluoren-2-yl-
Previous Indexing: Acetamides (1971-1974); Fluorenes (1966-1974)
Public MeSH Note: 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Online Note: use 2-ACETYLAMINOFLUORENE to search ACETYLAMINOFLUORENE 1975-82
History Note: 83; was ACETYLAMINOFLUORENE 1980-82; was ACETYLAMINOFLUORENE see under FLUORENES 1975-79
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0023186
Registry Number: 9M98QLJ2DL
Related Numbers: 53-96-3
Scope Note: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
Terms: 2-Acetylaminofluorene Preferred Term
Term UI T043970
Date01/01/1999
LexicalTag NON
ThesaurusID; 2-Acetamidofluorene
Term UI T043969
Date05/18/1982
LexicalTag NON
ThesaurusID UNK (19XX); 2-Fluorenylacetamide
Term UI T043973
Date02/08/1989
LexicalTag NON
ThesaurusID NLM (1989); N-2-Fluorenylacetamide
Term UI T043972
Date08/13/1980
LexicalTag NON
ThesaurusID; N-Acetyl-2-Aminofluorene
Term UI T837715
Date02/22/2013
LexicalTag NON
ThesaurusID NLM (2014); AAF, Aminofluorene
Term UI T837716
Date02/22/2013
LexicalTag ABX
ThesaurusID NLM (2014); 2-AAF
Term UI T043968
Date04/23/1981
LexicalTag ABB
ThesaurusID UNK (19XX); Fluoren-2-ylacetamide
Term UI T043971
Date05/18/1982
LexicalTag NON
ThesaurusID UNK (19XX)

2-Acetylaminofluorene MeSH Descriptor Data 2024