Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

2-Hydroxy-5-nitrobenzyl Bromide MeSH Descriptor Data 2025


MeSH Heading
2-Hydroxy-5-nitrobenzyl Bromide
Tree Number(s)
D02.455.426.559.389.140.400
D02.455.426.559.389.657.566.400
D02.640.743.400
Unique ID
D015077
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015077
Scope Note
A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Entry Term(s)
Koshland Reagent
Koshland's Reagent I
Koshlands Reagent
Pharm Action
Indicators and Reagents
Registry Numbers
772-33-8
CAS Type 1 Name
Phenol, 2-(bromomethyl)-4-nitro-
Previous Indexing
Benzyl Compounds (1973-1974)
Nitrophenols (1973-1974)
Public MeSH Note
91; was see under NITROPHENOLS 1975-90
History Note
91(75); was see under NITROPHENOLS 1975-90
Date Established
1991/01/01
Date of Entry
1974/11/19
Revision Date
2012/07/03
2-Hydroxy-5-nitrobenzyl Bromide Preferred
page delivered in 0.145s