MeSH Browser

MeSH Heading: 2-Hydroxy-5-nitrobenzyl Bromide
Tree Number(s): D02.455.426.559.389.140.400; D02.455.426.559.389.657.566.400; D02.640.743.400
Unique ID: D015077
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015077
Scope Note: A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Entry Term(s): Koshland Reagent; Koshland's Reagent I; Koshlands Reagent
Pharm Action: Indicators and Reagents
CAS Type 1 Name: Phenol, 2-(bromomethyl)-4-nitro-
Previous Indexing: Benzyl Compounds (1973-1974); Nitrophenols (1973-1974)
Public MeSH Note: 91; was see under NITROPHENOLS 1975-90
History Note: 91(75); was see under NITROPHENOLS 1975-90
Date Established: 1991/01/01
Date of Entry: 1974/11/19
Revision Date: 2012/07/03

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analogs & derivatives (AA)

analysis (AN)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

Concept UI: M0023190
Scope Note: A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as Koshland's reagent.
Terms: 2-Hydroxy-5-nitrobenzyl Bromide Preferred Term
Term UI T043980
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1975); Koshland's Reagent I
Term UI T043981
Date06/06/1988
LexicalTag EPO
ThesaurusID UNK (19XX); Koshlands Reagent
Term UI T043983
Date06/06/1988
LexicalTag EPO
ThesaurusID UNK (19XX); Koshland Reagent
Term UI T043982
Date06/06/1988
LexicalTag EPO
ThesaurusID UNK (19XX)

2-Hydroxy-5-nitrobenzyl Bromide MeSH Descriptor Data 2024