- Concept UI
- M0023862
- Registry Numbers
- EC 2.3.1.28
- Related Numbers
- 9040-07-7
- Scope Note
- An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 2.3.1.28.
- Terms
-
Chloramphenicol O-Acetyltransferase
Preferred Term
Term UI
T045977
Date01/01/1999
LexicalTag
NON
ThesaurusID
NLM (1989)
-
CAT Enzyme
Term UI
T045974
Date05/24/1988
LexicalTag
NON
ThesaurusID
UNK (19XX)
-
Chloramphenicol Acetyltransferase
Term UI
T045975
Date12/03/1996
LexicalTag
NON
ThesaurusID
NLM (1998)
-
Chloramphenicol Transacetylase
Term UI
T045976
Date05/24/1988
LexicalTag
NON
ThesaurusID
UNK (19XX)