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Inositol 1,4,5-Trisphosphate MeSH Descriptor Data 2022


MeSH Heading
Inositol 1,4,5-Trisphosphate
Tree Number(s)
D02.033.800.519.400.350
D09.853.519.400.350
D09.894.480.350
Unique ID
D015544
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015544
Scope Note
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.
Entry Term(s)
1,4,5-IP3
1,4,5-InsP3
Inositol 1,4,5-Triphosphate
Myo-Inositol 1,4,5-Trisphosphate
Myoinositol 1,4,5-Triphosphate
Registry Number
85166-31-0
CAS Type 1 Name
D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate)
Previous Indexing
Inositol Phosphates (1978-1989)
Sugar Phosphates (1974-1977)
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/07/05
Revision Date
2004/07/07
Inositol 1,4,5-Trisphosphate Preferred
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