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Cytochalasin D MeSH Descriptor Data 2024


MeSH Heading
Cytochalasin D
Tree Number(s)
D03.633.100.473.231.450
D23.946.587.370.450
Unique ID
D015638
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015638
Scope Note
A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
Pharm Action
Nucleic Acid Synthesis Inhibitors
Registry Number
22144-77-0
CAS Type 1 Name
(11)Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)-
Previous Indexing
Cytochalasins (1973-1989)
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/05/15
Revision Date
2016/05/28
Cytochalasin D Preferred
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