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Mifepristone MeSH Descriptor Data 2022


MeSH Heading
Mifepristone
Tree Number(s)
D04.210.500.365.415.580
Unique ID
D015735
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015735
Scope Note
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Entry Term(s)
Mifegyne
Mifeprex
Mifégyne
R-38486
R38486
RU-38486
RU-486
ZK-98296
ZK98296
Pharm Action
Abortifacient Agents, Steroidal
Contraceptives, Oral, Synthetic
Contraceptives, Postcoital, Synthetic
Hormone Antagonists
Luteolytic Agents
Menstruation-Inducing Agents
Registry Number
320T6RNW1F
Related Numbers
84371-65-3
CAS Type 1 Name
Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-, (11beta,17beta)-
Previous Indexing
Abortifacient Agents, Steroidal (1975-1989)
Contraceptives, Oral, Synthetic (1975-1989)
Estrenes (1975-1989)
Glucocorticoids/antagonists & inhibitors (1967-1989)
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/09/06
Revision Date
2017/05/24
Mifepristone Preferred
ZK-98296 Related
R-38486 Narrower
Mifegyne Narrower
Mifeprex Narrower
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