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4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine MeSH Descriptor Data 2022


MeSH Heading
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine
Tree Number(s)
D03.383.129.539.180
Unique ID
D015772
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015772
Scope Note
A dual inhibitor of both cyclooxygenase and lipoxygenase pathways. It exerts an anti-inflammatory effect by inhibiting the formation of prostaglandins and leukotrienes. The drug also enhances pulmonary hypoxic vasoconstriction and has a protective effect after myocardial ischemia.
Entry Term(s)
BW-755C
BW755C
Pharm Action
Anti-Inflammatory Agents, Non-Steroidal
Lipoxygenase Inhibitors
Cyclooxygenase Inhibitors
Registry Number
66000-40-6
CAS Type 1 Name
1H-Pyrazol-3-amine, 4,5-dihydro-1-(3-(trifluoromethyl)phenyl)-
Previous Indexing
Anti-Inflammatory Agents (1966-1986)
Anti-Inflammatory Agents, Non-Steroidal (1987-1989)
Pyrazoles (1966-1989)
Public MeSH Note
2005; see BW-775C 1996-2004; see BW 755C 1990; see BW-755C 1990-1995
History Note
2005(1991)
Date Established
1990/01/01
Date of Entry
1989/05/25
Revision Date
2018/06/30
4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine Preferred
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