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Complement C4b MeSH Descriptor Data 2023


MeSH Heading
Complement C4b
Tree Number(s)
D12.776.124.486.274.350.260
Unique ID
D015935
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015935
Scope Note
The large fragment formed when COMPLEMENT C4 is cleaved by COMPLEMENT C1S. The membrane-bound C4b binds COMPLEMENT C2A, a SERINE PROTEASE, to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Entry Term(s)
C4b Complement
Complement 4b
Complement Component 4b
Pharm Action
Immunologic Factors
Registry Number
80295-50-7
CAS Type 1 Name
Complement C4b
Previous Indexing
Complement 4 (1975-1989)
Public MeSH Note
2006; see COMPLEMENT 4B 1990-2005
History Note
2006 (1990)
Date Established
1990/01/01
Date of Entry
1989/05/25
Revision Date
2005/06/30
Complement C4b Preferred
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