A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.
Entry Term(s)
Post-Translational Isoprenylation
Protein Farnesylation
Protein Geranylgeranylation
Protein Isoprenylation
Protein Polyisoprenylation
Previous Indexing
Protein Processing, Post-Translational (1987-1992)
A post-translational modification of proteins by the attachment of an isoprenoid to the C-terminal cysteine residue. The isoprenoids used, farnesyl diphosphate or geranylgeranyl diphosphate, are derived from the same biochemical pathway that produces cholesterol.
